Dear colleague,

I am writing to inform you about an exciting clinical trial with Trichuris suis ova (pig whipworm eggs) for patients with Ulcerative colitis that we are conducting in the Division of Gastroenterology at Virginia Mason Medical Center. Pig whipworms have been previously shown to modulate the gut immune response while only transiently colonizing the human digestive system (generally the colon). No adverse events related to pig whipworms were described in human studies. The study is conducted under the auspices of the National Institute of Health and we are one of the participating sites.

Patients must have a diagnosis of left-sided ulcerative colitis and be mild to moderately symptomaticat the time of enrollment into the study. Patients may currently be receiving mesalamine-based drugs (such as Asacol, Lialda, sulfasalazine) and corticosteroids but they are not allowed to be on  immunomodulators (azathioprine, 6-MP, methotrexate) or biologics. They can be using natural products or supplements as long as the prescription is not changed during the study.

Patients should be willing to have one regular office visit and a flexible sigmoidoscopy on clinical grounds basis (i.e. covered by their own insurance) in order to verify their eligibility for the study.

If you have any patients who might be interested in this study, please let my office or my research coordinator know at the following phone numbers:


Dr. Michael Chiorean, MD                                            Tracey Pierce, CCRC

Division of Gastroenterology                                      Clinical Research Coordinator

Virginia Mason Medical Center                                  Digestive Disease Institute

Attn: Referral Coordinator                                           1100 Ninth Ave, D-4 CRP

1100 Ninth Ave, C-3 GAS                                               Seattle, WA 98101

Seattle, WA 98101                                                           (206) 341-1416

(206) 223-2319                                                    



Michael Chiorean, MD


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Philosophy of Natural Medicine

- Do no harm
- Find and treat the cause
- Treat the whole person
- Doctor as teacher
- The healing power of nature
- Promote wellness


- Preventive care may result in fewer sick days.
- Improved overall health and well-being (establishing a healthy diet and lifestyle program).
- Natural, non-invasive approach to illness (may reduce medication use).

Holiday Hours

The office will be closed Dec 31 - Jan 4, 2018 and will resume normal business hours on Jan 7, 2018.